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Essential Questions: Progesterone

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Over-The-Counter Hormone Solutions!

What really is Menopause?

Menopause is a natural biological process marking the end of a woman's reproductive years. It is diagnosed after a woman has gone 12 consecutive months without a menstrual period. Menopause typically occurs between the ages of 45 and 55, although it can happen earlier or later.

Main hormonal changes:

  1. Progesterone: Progesterone drops faster in midlife than estrogen. This is what leads to various symptoms including mood swings, sleep disturbances, and irregular menstrual cycles. In perimenopause, estrogen levels are now known to average 30% higher, to be chaotic, and to be associated with less progesterone.

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  1. Estrogen: Menopause means that ovarian production of estrogen declines to levels that do not induce a menstrual cycle. It is a natural phenomenon indicating only that one’s period of fertility is over. However, it does not mean estrogen has gone to zero. Since a woman's fat cells and skin cells still produce estrogen, estrogen levels often remain high. Estrogen continues to be produced, although in lesser amounts, by conversion of a sterol, androstenedione, which is found in fat, including the fat in muscle cells.

  2. Pregnenolone: Known as the "mother hormone," pregnenolone is a precursor to many other hormones. As women approach perimenopause, the production of pregnenolone in the body decreases. This decline contributes to the hormonal imbalances that characterize perimenopause, potentially exacerbating symptoms such as mood swings, fatigue, and cognitive changes.

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  1. DHEA: Levels of DHEA peak in early adulthood and begin to decline gradually with age. During perimenopause, the drop in DHEA can contribute to symptoms like decreased libido, reduced energy levels, and a decline in overall well-being. Lower DHEA levels are also associated with decreased bone density and muscle mass.

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  1. Cortisol

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  1. Low Thyroid:

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